Author Archives: Brain Research Lab
Stereological Study of Amygdala Glial Populations in Adolescents and Adults with Autism Spectrum Disorder
The amygdala undergoes aberrant development in autism spectrum disorder (ASD). We previously found that there [...]
Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
Sporadic Alzheimer’s disease (AD) is a multifactorial metabolic brain disorder characterized by progressive neurodegeneration. Decreased [...]
Effect of a chronic treatment with an mGlu5 receptor antagonist on brain serotonin markers in parkinsonian monkeys
In Parkinson's disease (PD) and l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesias (LIDs), overactivity of brain glutamate neurotransmission is [...]
Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice.
Decreased brain insulin signaling has been found recently in Alzheimer's disease (AD). Intranasal administration of [...]
Cortical innervation of the hypoglossal nucleus in the non-human primate (Macaca mulatta)
The corticobulbar projection to the hypoglossal nucleus was studied from the frontal, parietal, cingulate and [...]
Overexpression of Diacylglycerol Kinase η Enhances Gαq-Coupled G Protein–Coupled Receptor Signaling
Multiple genome-wide association studies have linked diacylglycerol kinase η(DGKη) to bipolar disorder (BPD).
Induction of cobalt accumulation by excitatory amino acids within neurons of the hippocampal slice. May 1992
Multiple genome-wide association studies have linked diacylglycerol kinase η(DGKη) to bipolar disorder (BPD).
Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction
Modern scientific knowledge of how memory functions are organized in the human brain originated from [...]
Long-term treatment with l-DOPA and an mGlu5 receptor antagonist prevents changes in brain basal ganglia dopamine receptors, their associated signaling proteins and neuropeptides in parkinsonian monkeys
Brain glutamate overactivity is well documented in Parkinson's disease (PD) and antiglutamatergic drugs decrease L-3,4-dihydroxyphenylalanine [...]
Chronic wheel running affects cocaine-induced c-Fos expression in brain reward areas in rats
Emerging evidence from human and animal studies suggests that exercise is a highly effective treatment [...]